CYTOFLU- Advanced & Novel Flucytosine
Flucytosine or 5-Fluorocytosine(5-FC) is one of the oldest antifungal drugs also sold under brand name of Ancobon and Ancotil to treat Cryptococcal Meningitis.
Flucytosine is effective as mono or combination therapy in treating infections caused by C. neoformans, Candida spp. and T. glabrata, chromoblastomycosis , phaeohyphomycosis, systemic mycoses, intrinsically resistant strains , chromoblastomycosis , urinary tract candidosis and vaginal candidosis.
There are number for reasons for treatment of deep-seated or systemic fungal infections which become very complex. Changes in Medical care and international travel has broadened the range of clinically necessary fungi. Moreover, prevalence of resistance to antifungal agents and immunosuppressant patients has increased and thus pushed for introduction of anti-fungal drugs like Flucytosine, Ketoconazole, Itraconazole, Fluconazole, Posaconazole, Voriconazole , Caspofungin & Amphotericin B.